I watched a few episodes of Bojack Horseman when it first aired and I just did not get it. Then Tabitha went to school and Charlotte binged it and then insisted I watch it.
I still found it a bit of a chore because it's just wave after wave of impulsive, self-destructive behaviour, but there's an arc in series 4 involving Bojack's mother and some other members of his family (trying to avoid overt spoilers) that finally tipped me over. It previously felt gratuitously heavy, but when all the foreshadowing converged it really tugged at my heart-strings.
Every time I think a character in this show is growing or making progress, they sabotage themselves and end up worse than they started off. I can't bring myself to admit how realistic that is.